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SPHERA FUNDS MANAGEMENT LTD. 13F 持仓明细(2026-03-31) · 小隐寺数据中心
SPHERA FUNDS MANAGEMENT LTD.
报告期 2026-03-31 · CIK 0001496201
持仓数
96
前50大市值合计
$518.3M
报告期
2026-03-31
当前持仓
调仓
组合演变
前 6 大持仓 + 其他 逐季市值($B) · 点图或下方季度看该季调仓
看某季调仓:
26Q1
25Q4
25Q3
25Q2
25Q1
24Q4
24Q3
24Q2
24Q1
23Q4
23Q3
23Q2
23Q1
22Q4
22Q3
22Q2
22Q1
21Q4
21Q3
21Q2
26Q1 调仓
2025-12-31 → 2026-03-31 · 共 104 项
建仓 20
增持 32
减持 29
清仓 23
方向
标的
Δ市值
现股数(环比)
增持
MLYS
MINERALYS THERAPEUTICS INC
+$20.0M
1,339,971
+198%
增持
XBI
SPDR SERIES TRUST
+$17.0M
200,000
+186%
增持
CYTK
CYTOKINETICS INC
+$13.9M
299,117
+226%
调仓由相邻两季 13F 持仓相减推导(非逐笔成交);方向按股数增减,Δ市值受股价波动影响、符号可与方向相反;13F 申报滞后最长 45 天。
清仓
—
ASTRAZENECA PLC
-$12.4M
0
-100%
建仓
—
ASTRAZENECA PLC
+$12.3M
62,530
清仓
PRAX
PRAXIS PRECISION MEDICINES I
-$11.8M
0
-100%
增持
—
TOWER SEMICONDUCTOR LTD
+$11.2M
145,735
+19%
增持
BBIO
BRIDGEBIO PHARMA INC
+$10.0M
245,246
+128%
建仓
—
CELLEBRITE DI LTD
+$8.7M
631,521
建仓
PANW
PALO ALTO NETWORKS INC
+$8.5M
52,800
建仓
ORA
ORMAT TECHNOLOGIES INC
+$7.6M
68,250
增持
—
NOVA LTD
+$7.5M
53,366
+12%
建仓
XENE
XENON PHARMACEUTICALS INC
+$7.4M
127,000
建仓
AMZN
AMAZON COM INC
+$6.7M
31,940
清仓
ANNX
ANNEXON INC
-$6.6M
0
-100%
建仓
AAOI
APPLIED OPTOELECTRONICS INC
+$6.2M
73,400
减持
NICE
NICE LTD
-$5.7M
5,611
-90%
建仓
—
BIOHAVEN LTD
+$5.0M
594,000
减持
DYN
DYNE THERAPEUTICS INC
-$4.8M
160,594
-59%
清仓
—
ASTRIA THERAPEUTICS INC
-$4.7M
0
-100%
建仓
ZBIO
ZENAS BIOPHARMA INC
+$4.2M
214,334
建仓
RLAY
RELAY THERAPEUTICS INC
+$4.1M
408,436
增持
PMN
PROMIS NEUROSCIENCES INC
+$4.1M
325,591
+2658%
清仓
AMD
ADVANCED MICRO DEVICES INC
-$3.9M
0
-100%
增持
—
CAMTEK LTD
+$3.8M
53,020
+34%
增持
MAZE
MAZE THERAPEUTICS INC
+$3.8M
227,343
+216%
建仓
OVID
OVID THERAPEUTICS INC
+$3.6M
1,622,828
清仓
TARA
PROTARA THERAPEUTICS INC
-$3.5M
0
-100%
建仓
IRON
DISC MEDICINE INC
+$3.4M
53,538
清仓
AVGO
BROADCOM INC
-$3.4M
0
-100%
建仓
UPB
UPSTREAM BIO INC
+$3.2M
358,000
清仓
—
ELBIT SYS LTD
-$3.1M
0
-100%
增持
PFE
PFIZER INC
+$3.1M
186,000
+116%
减持
SVRA
SAVARA INC
-$3.1M
739,164
-37%
减持
SEDG
SOLAREDGE TECHNOLOGIES INC
-$3.0M
52,836
-73%
增持
—
WAVE LIFE SCIENCES LTD
-$3.0M
548,272
+34%
增持
MDGL
MADRIGAL PHARMACEUTICALS INC
+$2.8M
9,040
+174%
建仓
MSLE
SATELLOS BIOSCIENCE INC
+$2.8M
489,207
增持
PALI
PALISADE BIO INC
+$2.6M
1,733,471
+842%
增持
COGT
COGENT BIOSCIENCES INC
+$2.6M
416,340
+10%
减持
ELVN
ENLIVEN THERAPEUTICS INC
+$2.5M
153,265
-32%
减持
TNGX
TANGO THERAPEUTICS INC
+$2.4M
343,563
-37%
清仓
NRIX
NURIX THERAPEUTICS INC
-$2.4M
0
-100%
减持
—
APELLIS PHARMACEUTICALS INC
+$2.3M
214,914
-14%
减持
SRRK
SCHOLAR ROCK HLDG CORP
-$2.3M
94,265
-40%
建仓
GENB
GENERATE BIOMEDICINES INC
+$2.3M
185,000
减持
ELDN
ELEDON PHARMACEUTICALS INC
+$2.2M
1,772,131
-17%
减持
—
IMMATICS N.V
-$2.2M
696,105
-19%
清仓
JANX
JANUX THERAPEUTICS INC
-$2.2M
0
-100%
清仓
TSHA
TAYSHA GENE THERAPIES INC
-$2.0M
0
-100%
增持
HELP
CYBIN INC
-$2.0M
987,090
+20%
增持
RARE
ULTRAGENYX PHARMACEUTICAL IN
+$2.0M
809,333
+24%
清仓
—
PHARVARIS N V
-$1.8M
0
-100%
清仓
VRNS
VARONIS SYS INC
-$1.7M
0
-100%
增持
BCRX
BIOCRYST PHARMACEUTICALS INC
+$1.7M
866,464
+3%
减持
BIOA
BIOAGE LABS INC
-$1.7M
86,518
-64%
清仓
—
VENTYX BIOSCIENCES INC
-$1.6M
0
-100%
增持
PRLD
PRELUDE THERAPEUTICS INC
+$1.6M
558,339
+355%
建仓
OLMA
OLEMA PHARMACEUTICALS INC
+$1.5M
100,000
增持
NVO
NOVO-NORDISK A S
-$1.5M
120,677
+4%
减持
DTIL
PRECISION BIOSCIENCES INC
-$1.4M
40,000
-90%
减持
ORIC
ORIC PHARMACEUTICALS INC
-$1.4M
537,628
-46%
增持
SNY
SANOFI SA
+$1.4M
269,515
+13%
清仓
—
DAY ONE BIOPHARMACEUTICALS I
-$1.4M
0
-100%
建仓
ORGO
ORGANOGENESIS HLDGS INC
+$1.3M
550,000
增持
CLDX
CELLDEX THERAPEUTICS INC NEW
+$1.2M
243,575
+2%
增持
RVMD
REVOLUTION MEDICINES INC
+$1.2M
55,110
+5%
清仓
TRDA
ENTRADA THERAPEUTICS INC
-$1.1M
0
-100%
增持
STTK
SHATTUCK LABS INC
+$1.1M
280,786
+44%
建仓
—
CURIS INC
+$1.1M
1,994,937
清仓
TNYA
TENAYA THERAPEUTICS INC
-$1.1M
0
-100%
减持
EVMN
EVOMMUNE INC
-$1.0M
78,234
-53%
建仓
CTMX
CYTOMX THERAPEUTICS INC.
+$1.0M
220,000
清仓
CATX
PERSPECTIVE THERAPEUTICS INC
-$962.4K
0
-100%
增持
—
SOLENO THERAPEUTICS INC
+$929.8K
216,281
+59%
减持
SNDX
SYNDAX PHARMACEUTICALS INC
+$904.3K
724,563
-5%
清仓
JSPR
JASPER THERAPEUTICS INC
-$888.3K
0
-100%
减持
CLYM
CLIMB BIO INC
-$857.1K
419,247
-55%
减持
BMRN
BIOMARIN PHARMACEUTICAL INC
-$833.3K
139,900
-5%
增持
TEVA
TEVA PHARMACEUTICAL INDS LTD
-$819.5K
1,136,975
+1%
增持
ABBV
ABBVIE INC
+$809.6K
30,256
+20%
增持
IBIT
ISHARES BITCOIN TRUST ETF
+$794.0K
59,505
+98%
清仓
PEPG
PEPGEN INC
-$790.8K
0
-100%
减持
—
AMICUS THERAPEUTIC
-$650.5K
603,377
-8%
减持
TRVI
TREVI THERAPEUTICS INC
-$645.5K
574,029
-4%
减持
ENPH
ENPHASE ENERGY INC
-$592.5K
142,419
-24%
减持
KOD
KODIAK SCIENCES INC
-$531.0K
114,796
-35%
减持
—
ASCENDIS PHARMA A/S
-$515.8K
8,000
-27%
减持
CRVS
CORVUS PHARMACEUTICALS INC
+$488.3K
247,961
-39%
增持
VYGR
VOYAGER THERAPEUTICS INC
+$478.0K
469,761
+38%
增持
GPCR
STRUCTURE THERAPEUTICS INC
-$403.0K
50,800
+24%
减持
VOR
VOR BIOPHARMA INC
+$374.7K
321,917
-22%
减持
JNJ
JOHNSON & JOHNSON
-$367.8K
28,831
-20%
减持
BIIB
BIOGEN INC
+$289.9K
92,526
-2%
减持
FBRX
FORTE BIOSCIENCES INC
-$277.6K
184,984
-0%
清仓
OKUR
ONKURE THERAPEUTICS INC
-$175.3K
0
-100%
增持
—
MEDIWOUND LTD
+$148.9K
273,192
+19%
减持
TENX
TENAX THERAPEUTICS INC
-$142.6K
136,015
-28%
清仓
MREO
MEREO BIOPHARMA GROUP PLC
-$106.4K
0
-100%
减持
—
ZIM INTEGRATED SHIPPING SERV
-$95.6K
105,950
-22%
建仓
FHTX
FOGHORN THERAPEUTICS INC
+$58.4K
12,224
增持
SKYE
SKYE BIOSCIENCE INC
+$58.2K
678,928
+42%
增持
ACAD
ACADIA PHARMACEUTICALS INC
+$35.1K
256,202
+21%
清仓
—
APPLIED THERAPEUTICS INC
-$5.0K
0
-100%
