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SPHERA FUNDS MANAGEMENT LTD. 13F 持仓明细(2026-03-31) · 小隐寺数据中心
SPHERA FUNDS MANAGEMENT LTD.
报告期 2026-03-31 · CIK 0001496201
持仓数
96
前50大市值合计
$518.3M
报告期
2026-03-31
当前持仓
调仓
组合演变
前 6 大持仓 + 其他 逐季市值($B) · 点图或下方季度看该季调仓
看某季调仓:
26Q1
25Q4
25Q3
25Q2
25Q1
24Q4
24Q3
24Q2
24Q1
23Q4
23Q3
23Q2
23Q1
22Q4
22Q3
22Q2
22Q1
21Q4
21Q3
21Q2
25Q4 调仓
2025-09-30 → 2025-12-31 · 共 114 项
建仓 24
增持 32
减持 27
清仓 31
方向
标的
Δ市值
现股数(环比)
清仓
—
CIDARA THERAPEUTICS INC
-$16.8M
0
-100%
减持
NICE
NICE LTD
-$16.5M
55,700
-65%
清仓
—
MERUS N V
-$14.1M
0
-100%
调仓由相邻两季 13F 持仓相减推导(非逐笔成交);方向按股数增减,Δ市值受股价波动影响、符号可与方向相反;13F 申报滞后最长 45 天。
清仓
QQQ
INVESCO QQQ TR
-$13.8M
0
-100%
增持
COGT
COGENT BIOSCIENCES INC
+$12.0M
378,500
+284%
增持
SNDX
SYNDAX PHARMACEUTICALS INC
+$10.1M
762,563
+97%
建仓
BMRN
BIOMARIN PHARMACEUTICAL INC
+$8.7M
147,000
建仓
XBI
SPDR SERIES TRUST
+$8.5M
70,000
减持
—
TOWER SEMICONDUCTOR LTD
-$8.2M
122,513
-61%
增持
MLYS
MINERALYS THERAPEUTICS INC
+$8.0M
449,003
+104%
建仓
SRRK
SCHOLAR ROCK HLDG CORP
+$7.0M
158,265
增持
—
WAVE LIFE SCIENCES LTD
+$6.6M
408,166
+716%
建仓
BCRX
BIOCRYST PHARMACEUTICALS INC
+$6.5M
837,889
减持
PRAX
PRAXIS PRECISION MEDICINES I
+$6.1M
40,000
-63%
清仓
—
UNIQURE NV
-$5.8M
0
-100%
清仓
—
CELLEBRITE DI LTD
-$5.5M
0
-100%
建仓
VOR
VOR BIOPHARMA INC
+$5.4M
410,417
增持
BIIB
BIOGEN INC
+$5.1M
94,738
+15%
增持
ENPH
ENPHASE ENERGY INC
+$5.0M
186,500
+599%
建仓
KOD
KODIAK SCIENCES INC
+$4.9M
175,500
增持
—
APELLIS PHARMACEUTICALS INC
+$4.9M
250,961
+294%
建仓
TNGX
TANGO THERAPEUTICS INC
+$4.8M
544,563
清仓
RAPP
RAPPORT THERAPEUTICS INC
-$4.7M
0
-100%
减持
TEVA
TEVA PHARMACEUTICAL INDS LTD
+$4.6M
1,123,525
-25%
增持
HELP
CYBIN INC
+$4.6M
825,576
+123%
增持
RARE
ULTRAGENYX PHARMACEUTICAL IN
+$4.4M
650,623
+85%
清仓
IMVT
IMMUNOVANT INC
-$4.1M
0
-100%
增持
—
IMMATICS N.V
+$4.1M
861,105
+48%
增持
—
SOLENO THERAPEUTICS INC
+$3.5M
136,314
+228%
建仓
TARA
PROTARA THERAPEUTICS INC
+$3.5M
650,000
清仓
—
ENGENE HOLDINGS INC
-$3.4M
0
-100%
清仓
RZLT
REZOLUTE INC
-$3.4M
0
-100%
减持
GPCR
STRUCTURE THERAPEUTICS INC
-$3.4M
41,000
-82%
建仓
BIOA
BIOAGE LABS INC
+$3.2M
243,035
减持
CYTK
CYTOKINETICS INC
-$3.0M
91,717
-43%
增持
ORIC
ORIC PHARMACEUTICALS INC
+$3.0M
1,004,378
+133%
清仓
AMZN
AMAZON COM INC
-$3.0M
0
-100%
清仓
—
ROIVANT SCIENCES LTD
-$2.9M
0
-100%
清仓
SRPT
SAREPTA THERAPEUTICS INC
-$2.9M
0
-100%
建仓
—
ZIM INTEGRATED SHIPPING SERV
+$2.9M
136,005
清仓
META
META PLATFORMS INC
-$2.9M
0
-100%
增持
CLYM
CLIMB BIO INC
+$2.9M
932,247
+114%
建仓
EVMN
EVOMMUNE INC
+$2.8M
166,147
增持
—
ASTRIA THERAPEUTICS INC
+$2.8M
355,725
+42%
清仓
ORA
ORMAT TECHNOLOGIES INC
-$2.8M
0
-100%
清仓
IDYA
IDEAYA BIOSCIENCES INC
-$2.7M
0
-100%
减持
VRNS
VARONIS SYS INC
-$2.5M
52,500
-29%
增持
ACAD
ACADIA PHARMACEUTICALS INC
+$2.5M
212,202
+43%
清仓
TVTX
TRAVERE THERAPEUTICS INC
-$2.4M
0
-100%
建仓
NRIX
NURIX THERAPEUTICS INC
+$2.4M
124,000
建仓
—
ASCENDIS PHARMA A/S
+$2.3M
11,000
建仓
TENX
TENAX THERAPEUTICS INC
+$2.3M
190,111
减持
DYN
DYNE THERAPEUTICS INC
+$2.3M
392,894
-8%
减持
SVRA
SAVARA INC
+$2.3M
1,178,164
-13%
清仓
CEVA
CEVA INC
-$2.1M
0
-100%
减持
LLY
ELI LILLY & CO
+$2.1M
9,040
-10%
减持
FBRX
FORTE BIOSCIENCES INC
-$2.0M
185,869
-61%
建仓
CTNM
CONTINEUM THERAPEUTICS INC
+$2.0M
173,475
增持
VSTM
VERASTEM INC
+$2.0M
343,678
+339%
建仓
MDGL
MADRIGAL PHARMACEUTICALS INC
+$1.9M
3,300
清仓
TECX
TECTONIC THERAPEUTIC INC
-$1.8M
0
-100%
清仓
PCVX
VAXCYTE INC
-$1.8M
0
-100%
清仓
IMNM
IMMUNOME INC
-$1.7M
0
-100%
增持
—
NOVA LTD
+$1.7M
47,846
+9%
建仓
DTIL
PRECISION BIOSCIENCES INC
+$1.6M
396,116
清仓
MIST
MILESTONE PHARMACEUTICALS IN
-$1.6M
0
-100%
减持
—
AMICUS THERAPEUTICS INC
+$1.6M
658,377
-34%
增持
ACOG
ALPHA COGNITION INC
+$1.5M
567,616
+68%
减持
RVMD
REVOLUTION MEDICINES INC
+$1.4M
52,500
-13%
清仓
—
BIOHAVEN LTD
-$1.4M
0
-100%
增持
AMD
ADVANCED MICRO DEVICES INC
+$1.4M
18,040
+17%
清仓
BCAX
BICARA THERAPEUTICS INC
-$1.4M
0
-100%
增持
SNY
SANOFI SA
+$1.2M
239,515
+9%
增持
AVGO
BROADCOM INC
+$1.2M
9,755
+49%
减持
—
PHARVARIS N V
-$1.2M
63,953
-46%
增持
—
CAMTEK LTD
+$1.1M
39,498
+36%
建仓
TRDA
ENTRADA THERAPEUTICS INC
+$1.1M
110,942
清仓
SABS
SAB BIOTHERAPEUTICS INC
-$1.1M
0
-100%
增持
CLDX
CELLDEX THERAPEUTICS INC NEW
+$1.1M
239,764
+15%
减持
ANNX
ANNEXON INC
+$1.1M
1,316,212
-27%
建仓
TNYA
TENAYA THERAPEUTICS INC
+$1.1M
1,500,000
减持
MAZE
MAZE THERAPEUTICS INC
-$1.0M
71,843
-53%
增持
—
MEDIWOUND LTD
+$913.6K
230,347
+24%
增持
KURA
KURA ONCOLOGY INC
+$897.6K
295,522
+20%
清仓
LRMR
LARIMAR THERAPEUTICS INC
-$841.0K
0
-100%
减持
CATX
PERSPECTIVE THERAPEUTICS INC
-$788.0K
349,973
-31%
建仓
STTK
SHATTUCK LABS INC
+$712.5K
195,212
减持
TSHA
TAYSHA GENE THERAPIES INC
+$690.2K
368,146
-10%
减持
BBIO
BRIDGEBIO PHARMA INC
-$627.1K
107,746
-37%
增持
ELDN
ELEDON PHARMACEUTICALS INC
-$614.3K
2,132,131
+44%
减持
JSPR
JASPER THERAPEUTICS INC
-$609.9K
485,401
-23%
清仓
—
89BIO INC
-$583.2K
0
-100%
清仓
MLTX
MOONLAKE IMMUNOTHERAPEUTICS
-$580.8K
0
-100%
清仓
CMMB
CHEMOMAB THERAPEUTICS LTD
-$471.9K
0
-100%
增持
SEDG
SOLAREDGE TECHNOLOGIES INC
+$454.3K
196,536
+39%
建仓
PALI
PALISADE BIO INC
+$432.6K
184,100
清仓
ARWR
ARROWHEAD PHARMACEUTICALS IN
-$431.0K
0
-100%
减持
TRVI
TREVI THERAPEUTICS INC
+$419.3K
598,534
-23%
增持
VYGR
VOYAGER THERAPEUTICS INC
+$402.4K
339,761
+70%
建仓
PRLD
PRELUDE THERAPEUTICS INC
+$356.0K
122,752
减持
—
ELBIT SYS LTD
-$351.1K
5,340
-21%
减持
—
VENTYX BIOSCIENCES INC
+$257.7K
180,114
-59%
减持
AMGN
AMGEN INC
-$226.1K
7,500
-21%
清仓
DSGN
DESIGN THERAPEUTICS INC
-$165.0K
0
-100%
减持
JNJ
JOHNSON & JOHNSON
-$155.7K
35,831
-12%
清仓
—
PROMIS NEUROSCIENCES INC
-$125.5K
0
-100%
减持
—
DAY ONE BIOPHARMACEUTICALS I
+$118.5K
145,371
-17%
建仓
MREO
MEREO BIOPHARMA GROUP PLC
+$106.4K
255,400
增持
IBIT
ISHARES BITCOIN TRUST ETF
+$97.7K
30,055
+40%
建仓
PMN
PROMIS NEUROSCIENCES INC
+$80.6K
11,807
增持
JANX
JANUX THERAPEUTICS INC
+$80.3K
157,840
+84%
增持
ELVN
ENLIVEN THERAPEUTICS INC
+$78.5K
226,765
+36%
增持
NVO
NOVO-NORDISK A S
+$21.6K
115,677
+9%
减持
PEPG
PEPGEN INC
-$1.4K
121,467
-29%
