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SPHERA FUNDS MANAGEMENT LTD. 13F 持仓明细(2026-03-31) · 小隐寺数据中心
SPHERA FUNDS MANAGEMENT LTD.
报告期 2026-03-31 · CIK 0001496201
持仓数
96
前50大市值合计
$518.3M
报告期
2026-03-31
当前持仓
调仓
组合演变
前 6 大持仓 + 其他 逐季市值($B) · 点图或下方季度看该季调仓
看某季调仓:
26Q1
25Q4
25Q3
25Q2
25Q1
24Q4
24Q3
24Q2
24Q1
23Q4
23Q3
23Q2
23Q1
22Q4
22Q3
22Q2
22Q1
21Q4
21Q3
21Q2
21Q3 调仓
2021-06-30 → 2021-09-30 · 共 138 项
建仓 33
增持 29
减持 25
清仓 51
方向
标的
Δ市值
现股数(环比)
清仓
MRK
MERCK & CO INC
-$120.2M
0
-100%
建仓
PFE
PFIZER INC
+$47.6M
1,106,528
增持
XENE
XENON PHARMACEUTICALS INC
-$45.7M
373,510
+35%
调仓由相邻两季 13F 持仓相减推导(非逐笔成交);方向按股数增减,Δ市值受股价波动影响、符号可与方向相反;13F 申报滞后最长 45 天。
清仓
ENPH
ENPHASE ENERGY INC
-$42.2M
0
-100%
清仓
IGV
ISHARES TR
-$41.0M
0
-100%
增持
LLY
LILLY ELI & CO
+$38.8M
348,495
+92%
减持
XBI
SPDR SER TR
-$34.3M
400,000
-36%
清仓
XLK
SELECT SECTOR SPDR TR
-$31.0M
0
-100%
建仓
BMY
BRISTOL-MYERS SQUIBB CO
+$29.6M
500,000
减持
JNJ
JOHNSON & JOHNSON
-$28.2M
238,948
-41%
清仓
—
FIVERR INTL LTD
-$24.4M
0
-100%
增持
ABBV
ABBVIE INC
+$23.1M
596,294
+63%
增持
IWM
ISHARES TR
+$21.9M
210,000
+100%
清仓
TAN
INVESCO EXCH TRADED FD TR II
-$18.8M
0
-100%
增持
ALT
ALTIMMUNE INC
+$16.9M
2,088,854
+206%
建仓
PANW
PALO ALTO NETWORKS INC
+$14.8M
31,000
减持
—
ESSA PHARMA INC
-$14.8M
469,402
-28%
减持
GNRC
GENERAC HLDGS INC
-$14.3M
71,013
-32%
清仓
—
LIVEPERSON INC
-$14.2M
0
-100%
减持
AMZN
AMAZON COM INC
-$13.4M
161
-96%
清仓
VRNS
VARONIS SYS INC
-$12.6M
0
-100%
建仓
BMRN
BIOMARIN PHARMACEUTICAL INC
+$11.5M
149,017
减持
BIIB
BIOGEN INC
-$11.5M
50,000
-32%
清仓
—
ATERIAN INC
-$11.1M
0
-100%
建仓
—
WIX COM LTD
+$10.7M
11,100,000
建仓
—
IMMATICS N.V
+$10.4M
800,043
清仓
—
THERAPEUTICS ACQUISITION COR
-$10.4M
0
-100%
建仓
—
OMEGA THERAPEUTICS INC
+$10.0M
527,948
建仓
NKE
NIKE INC
+$9.4M
65,000
增持
—
ASTRAZENECA PLC
+$8.8M
1,291,667
+13%
减持
TEVA
TEVA PHARMACEUTICAL INDS LTD
-$8.8M
1,882,878
-31%
增持
KYMR
KYMERA THERAPEUTICS INC
+$8.5M
359,260
+38%
减持
NICE
NICE LTD
-$8.3M
37,786
-51%
清仓
NKTX
NKARTA INC
-$8.0M
0
-100%
清仓
STTK
SHATTUCK LABS INC
-$7.9M
0
-100%
减持
—
KORNIT DIGITAL LTD
-$7.9M
72,076
-51%
增持
—
GRAPHITE BIO INC
+$7.9M
531,269
+2029%
清仓
ONTO
ONTO INNOVATION INC
-$7.9M
0
-100%
清仓
STOK
STOKE THERAPEUTICS INC
-$7.8M
0
-100%
建仓
ADSK
AUTODESK INC
+$7.8M
27,500
清仓
—
MIRATI THERAPEUTICS INC
-$7.6M
0
-100%
增持
—
VINCERX PHARMA INC
+$7.6M
654,572
+188%
清仓
ONC
BEIGENE LTD
-$7.2M
0
-100%
建仓
CLDX
CELLDEX THERAPEUTICS INC NEW
+$7.0M
130,330
清仓
NRIX
NURIX THERAPEUTICS INC
-$6.5M
0
-100%
清仓
AGIO
AGIOS PHARMACEUTICALS INC
-$6.4M
0
-100%
建仓
TEAD
OUTBRAIN INC
+$6.4M
431,194
建仓
—
BIOATLA INC
+$6.3M
214,300
建仓
—
ZENDESK INC
+$6.3M
53,910
清仓
—
ORCHARD THERAPEUTICS PLC
-$6.0M
0
-100%
建仓
—
POINT BIOPHARMA GLOBAL INC
+$5.7M
739,190
清仓
SPRY
SILVERBACK THERAPEUTICS INC
-$5.4M
0
-100%
减持
NTLA
INTELLIA THERAPEUTICS INC
-$5.3M
23,647
-55%
建仓
CALX
CALIX INC
+$5.2M
105,290
增持
—
INHIBRX INC
+$5.1M
310,077
+64%
增持
IONS
IONIS PHARMACEUTICALS INC
+$5.0M
372,000
+99%
增持
SNDX
SYNDAX PHARMACEUTICALS INC
+$4.9M
750,603
+37%
建仓
CRBU
CARIBOU BIOSCIENCES INC
+$4.8M
200,000
清仓
—
CURIS INC
-$4.7M
0
-100%
减持
—
IVERIC BIO INC
+$4.7M
485,001
-3%
增持
—
ARYA SCIENCES ACQU CORP IV
+$4.7M
1,000,000
+100%
建仓
—
AMICUS THERAPEUTICS INC
+$4.7M
491,159
增持
PTGX
PROTAGONIST THERAPEUTICS INC
-$4.6M
510,379
+68%
增持
SEDG
SOLAREDGE TECHNOLOGIES INC
+$4.4M
50,000
+55%
增持
RUN
SUNRUN INC
+$4.3M
189,000
+163%
减持
DYN
DYNE THERAPEUTICS INC
-$4.1M
225,083
-39%
减持
—
ONCORUS INC
-$4.1M
880,702
-1%
建仓
—
IRONSOURCE LTD
+$4.0M
367,070
减持
—
AFFIMED N V
-$3.9M
1,117,619
-12%
清仓
NBP
I MAB
-$3.9M
0
-100%
清仓
—
SIGILON THERAPEUTICS INC
-$3.9M
0
-100%
建仓
—
ALIGOS THERAPEUTICS INC
+$3.9M
249,197
建仓
—
DYNAVAX TECHNOLOGIES CORP
+$3.8M
198,880
清仓
BEAM
BEAM THERAPEUTICS INC
-$3.7M
0
-100%
清仓
PLTK
PLAYTIKA HLDG CORP
-$3.6M
0
-100%
建仓
—
IMMUNIC INC
+$3.5M
389,812
增持
—
UNIQURE NV
+$3.4M
272,000
+58%
清仓
ARKO
ARKO CORP
-$3.4M
0
-100%
减持
KURA
KURA ONCOLOGY INC
-$3.3M
788,735
-9%
建仓
—
LESLIES INC
+$3.1M
150,000
清仓
—
GRACELL BIOTECHNOLOGIES INC
-$3.0M
0
-100%
清仓
—
TREMOR INTL LTD
-$3.0M
0
-100%
清仓
S
SENTINELONE INC
-$2.9M
0
-100%
建仓
—
OTONOMO TECHNOLOGIES LTD
+$2.9M
600,000
增持
PMVP
PMV PHARMACEUTICALS INC
+$2.8M
190,525
+127%
建仓
—
DICE THERAPEUTICS INC
+$2.8M
85,000
清仓
—
FREQUENCY THERAPEUTICS INC
-$2.7M
0
-100%
建仓
—
HIPPO HLDGS INC
+$2.6M
564,967
减持
CCCC
C4 THERAPEUTICS INC
-$2.6M
381,774
-26%
减持
—
AUDIOCODES LTD
-$2.4M
316,428
-18%
清仓
—
PERRIGO CO PLC
-$2.4M
0
-100%
清仓
TWST
TWIST BIOSCIENCE CORP
-$2.4M
0
-100%
清仓
—
CEREVEL THERAPEUTICS HLDNG I
-$2.4M
0
-100%
减持
—
VISTAGEN THERAPEUTICS INC
-$2.4M
3,824,938
-6%
增持
IOVA
IOVANCE BIOTHERAPEUTICS INC
+$2.4M
494,809
+31%
清仓
IPSC
CENTURY THERAPEUTICS INC
-$2.3M
0
-100%
增持
META
FACEBOOK INC
+$2.3M
34,400
+27%
建仓
—
ARYA SCIENCES ACQUISITN CORP
+$2.0M
200,000
清仓
—
HEALTHCOR CATALIO ACQU CORP
-$2.0M
0
-100%
清仓
—
HEALTHCARE CAPITAL CORP
-$2.0M
0
-100%
增持
ZLAB
ZAI LAB LTD
-$1.9M
145,982
+49%
建仓
AMAT
APPLIED MATLS INC
+$1.9M
14,500
清仓
ALDX
ALDEYRA THERAPEUTICS INC
-$1.7M
0
-100%
清仓
—
WIX COM LTD
-$1.7M
0
-100%
建仓
MOLN
MOLECULAR PARTNERS AG
+$1.6M
80,555
建仓
ERAS
ERASCA INC
+$1.5M
70,000
清仓
PLRX
PLIANT THERAPEUTICS INC
-$1.5M
0
-100%
清仓
—
SINGULAR GENOMICS SYSTEMS IN
-$1.5M
0
-100%
清仓
—
CLARIM ACQUISITION CORP
-$1.5M
0
-100%
清仓
—
PRAXIS PRECISION MEDICINES I
-$1.4M
0
-100%
增持
FATE
FATE THERAPEUTICS INC
-$1.3M
219,299
+33%
清仓
—
DFP HEALTHCARE ACQUISITNS CO
-$1.3M
0
-100%
清仓
—
LEFTERIS ACQUISITION CORP
-$1.1M
0
-100%
清仓
CELC
CELCUITY INC
-$1.1M
0
-100%
减持
ANNX
ANNEXON INC
-$1.0M
123,637
-17%
减持
ALXO
ALX ONCOLOGY HLDGS INC
-$1.0M
128,706
-33%
清仓
—
LIONHEART ACQUISITION CORP I
-$986.0K
0
-100%
清仓
—
E MERGE TECHNOLOGY ACQUISITI
-$976.0K
0
-100%
减持
—
ACHILLES THERAPEUTICS PLC
-$972.0K
242,500
-17%
增持
MGIC
MAGIC SOFTWARE ENTERPRISES L
+$895.0K
57,704
+261%
增持
TWLO
TWILIO INC
+$881.0K
35,500
+34%
建仓
—
AC IMMUNE SA
+$812.0K
121,019
增持
—
MERUS N V
+$770.0K
309,427
+8%
清仓
—
APOLLO STRATEGIC GROWTH CAPT
-$714.0K
0
-100%
减持
—
YUMANITY THERAPEUTICS INC
-$560.0K
75,836
-34%
减持
IDYA
IDEAYA BIOSCIENCES INC
+$483.0K
294,619
-12%
清仓
—
TAILWIND INTERNATNAL ACQ COR
-$483.0K
0
-100%
建仓
UPWK
UPWORK INC
+$450.0K
10,000
增持
—
ALLOT LTD
-$409.0K
341,067
+23%
清仓
—
ELEVATION ONCOLOGY INC
-$407.0K
0
-100%
减持
CRNX
CRINETICS PHARMACEUTICALS IN
-$404.0K
548,643
-13%
增持
GLUE
MONTE ROSA THERAPEUTICS INC
+$396.0K
119,647
+20%
增持
—
SPRINGWORKS THERAPEUTICS INC
-$352.0K
247,917
+27%
增持
—
CYTEIR THERAPEUTICS INC
-$303.0K
135,145
+8%
清仓
—
CEREVEL THERAPEUTICS HLDNG I
-$236.0K
0
-100%
减持
HOWL
WEREWOLF THERAPEUTICS INC
-$235.0K
688,475
-3%
建仓
IMCR
IMMUNOCORE HLDGS PLC
+$157.0K
4,235
建仓
—
LOGICBIO THERAPEUTICS INC
+$110.0K
24,042
