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BAKER BROS. ADVISORS LP 13F 持仓明细(2026-03-31) · 小隐寺数据中心

BAKER BROS. ADVISORS LP

报告期 2026-03-31 · CIK 0001263508

持仓数

84

前50大市值合计

$17.06B

报告期

2026-03-31

当前持仓调仓

组合演变前 6 大持仓 + 其他逐季市值($B) · 点图或下方季度看该季调仓

看某季调仓:

26Q1 25Q4 25Q3 25Q2 25Q1 24Q4 24Q3 24Q2 24Q1 23Q4 23Q3 23Q2 23Q1 22Q4

23Q4 调仓2023-09-30 → 2023-12-31 · 共 62 项建仓 5增持 23减持 12清仓 22

方向

标的

Δ市值

现股数(环比)

清仓

— Seagen Inc.

-$9.45B

0 -100%

清仓

BMRN BioMarin Pharmaceutical Inc.

-$337.1M

0 -100%

增持

MDGL Madrigal Pharmaceuticals, Inc.

+$230.1M

1,969,798 +27%

调仓由相邻两季 13F 持仓相减推导(非逐笔成交);方向按股数增减,Δ市值受股价波动影响、符号可与方向相反;13F 申报滞后最长 45 天。

减持

ONC BeiGene, Ltd.

-$192.7M

10,568,897 -9%

增持

INCY Incyte Corporation

+$181.7M

36,179,122 +0%

增持

— Mirati Therapeutics, Inc.

+$180.7M

4,121,440 +192%

减持

RYTM Rhythm Pharmaceuticals, Inc.

+$140.5M

6,398,365 -5%

增持

KYMR Kymera Therapeutics, Inc.

+$86.6M

5,995,928 +26%

增持

RVMD Revolution Medicines, Inc.

+$73.2M

5,148,657 +91%

清仓

— SpringWorks Therapeutics, Inc.

-$69.4M

0 -100%

建仓

— Cerevel Therapeutics Holdings, Inc.

+$67.8M

1,600,000

减持

— Roivant Sciences Ltd.

-$53.5M

7,593,024 -36%

增持

ABCL AbCellera Biologics Inc.

+$35.3M

22,909,753 +10%

增持

SERA Sera Prognostics, Inc.

+$29.7M

5,434,399 +259%

减持

BCRX BioCryst Pharmaceuticals, Inc.

-$29.3M

10,126,176 -20%

增持

EWTX Edgewise Therapeutics, Inc.

+$28.0M

3,112,786 +197%

减持

CABA Cabaletta Bio, Inc.

-$24.0M

13,331 -99%

增持

RARE Ultragenyx Pharmaceutical Inc.

+$21.4M

1,466,547 +7%

增持

XENE Xenon Pharmaceuticals Inc.

+$20.1M

993,679 +32%

增持

— Gracell Biotechnologies Inc.

+$18.0M

2,080,000 +108%

增持

BCYC Bicycle Therapeutics plc

+$15.4M

1,790,390 +112%

增持

CERS Cerus Corporation

+$14.1M

19,477,339 +13%

清仓

COGT Cogent Biosciences, Inc.

-$12.6M

0 -100%

减持

— Aerovate Therapeutics, Inc.

+$11.4M

1,680,517 -14%

建仓

CLDX Celldex Therapeutics, Inc.

+$9.8M

247,644

清仓

PACB Pacific Biosciences of California, Inc.

-$9.4M

0 -100%

建仓

NGNE Neurogene Inc.

+$8.8M

453,516

增持

DNLI Denali Therapeutics Inc.

+$8.7M

2,607,196 +14%

清仓

HRTX Heron Therapeutics, Inc.

-$8.4M

0 -100%

清仓

ARVN Arvinas, Inc.

-$8.1M

0 -100%

清仓

— bluebird bio, Inc.

-$7.6M

0 -100%

清仓

GERN Geron Corporation

-$6.5M

0 -100%

清仓

ALEC Alector, Inc.

-$6.3M

0 -100%

清仓

SMMT Summit Therapeutics Inc.

-$5.9M

0 -100%

清仓

— Morphic Holding, Inc.

-$4.9M

0 -100%

清仓

— Neoleukin Therapeutics, Inc.

-$4.8M

0 -100%

增持

STOK Stoke Therapeutics, Inc.

+$4.8M

2,030,134 +37%

增持

VERV Verve Therapeutics, Inc.

+$4.8M

1,691,530 +19%

清仓

NTRA Natera, Inc.

-$4.4M

0 -100%

增持

— IGM Biosciences, Inc.

+$4.3M

3,691,011 +17%

减持

WHWK Aadi Bioscience, Inc.

-$4.3M

251,727 -75%

增持

— Immatics N.V.

-$3.8M

5,838,853 +4%

减持

— Opthea Limited

+$2.9M

2,588,645 -4%

增持

XNCR Xencor, Inc.

+$2.7M

245,431 +99%

增持

REPL Replimune Group, Inc.

+$2.1M

9,545,336 +108%

清仓

— Affimed N.V.

-$2.1M

0 -100%

清仓

— Instil Bio, Inc.

-$2.0M

0 -100%

清仓

ANAB AnaptysBio, Inc.

-$1.9M

0 -100%

清仓

— POINT Biopharma Global Inc.

-$1.7M

0 -100%

清仓

— iTeos Therapeutics, Inc.

-$1.6M

0 -100%

增持

— HOOKIPA Pharma Inc.

+$1.6M

8,128,151 +1%

清仓

— Vor Biopharma Inc.

-$1.3M

0 -100%

清仓

— Avidity Biosciences, Inc.

-$1.1M

0 -100%

建仓

PFE Pfizer Inc.

+$1.0M

35,000

增持

TSHA Taysha Gene Therapies, Inc.

-$826.6K

4,004,756 +60%

增持

SGMT Sagimet Biosciences Inc.

+$719.2K

1,456,518 +79%

减持

— Atreca, Inc.

-$634.6K

2,177,499 -38%

减持

— Achilles Therapeutics plc

-$457.4K

2,102,792 -18%

清仓

— Genetron Holdings Limited

-$369.8K

0 -100%

减持

IPSC Century Therapeutics, Inc.

+$348.9K

797,460 -31%

减持

— Praxis Precision Medicines, Inc.

-$284.1K

131,533 -93%

建仓

TYRA Tyra Biosciences, Inc.

+$146.9K

10,607